Question: My father is diagnosed with Waldenstrom's macroglobulinemia and was suffering from low haemoglobin levels due to it. He was treated with Rituximab (Mabthera) in 2004 followed by injections of Erythropoetin (Neorecormon) on regular basis. As a result his haemoglobin level stabilized at 11. Since last 2 months his haemoglobin level has again started decreasing, around 7, for which he received blood transfusion of one unit recently. Now the doctor has advised treatment with Rituximab in combination with flubardin. Could you please comment on the line of treatment.