AB Negative Blood

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AB negative blood is extremely rare; only 1 out of 10,000 babies born each year have it.

The leading cause of having AB negative blood is the absence of the gene responsible for producing ABO blood group antigens. Two genes are responsible for producing these antigens; one is located on chromosome 9, and the other on chromosome 4. If both genes are absent, the individual does not produce antigens.

But is AB-negative blood safe, and what is unique about it? Find answers to all this and more in this blog.

What is AB Negative Blood?

AB Negative blood is hemoglobin with no A or B protein chains. Instead, it has two different globin chains that produce red blood cells with less oxygen-carrying capacity than normal red blood cells. 

Is AB Negative Rare?

Less than 1% of Americans have an AB- blood type, making it a rare blood type in the country. All negative blood types can donate red blood cells to patients with AB- negative blood types. If both parents have AB-negative blood, their offspring will likely inherit the same trait.

AB negative blood is not only rare but also extremely valuable. It contains many different types of antibodies that help protect the body from disease-causing organisms. The lack of these antibodies makes a person susceptible to illness and infection.

AB blood type contains antibodies immune system cells that fight off foreign invaders and infections. Blood types A, B, O, and AB have different amounts of each antibody.

AB Blood has A B antigens attached to its red blood cells. These antigens are what makes them different than any other blood type. When someone gets their first vaccination, they get a shot of blood that contains these antigens. If they have been vaccinated before then, they will not react to the vaccine.

If a person does not have suitable antibodies in their body, they cannot fight off infections. People with blood type AB have more antibodies. This means they are less likely to get sick.

However, if someone does get sick, their body will make more antibodies to protect them.

People who do not have AB blood need to receive transfusions. Only 1% of the people have AB blood type, making it the rarest body type.

Here are some less-known facts about AB negative blood. 

1. AB negative blood is not harmful to humans.

AB negative blood is normal and does not carry any risks to human health. There have been instances where people born with AB negative blood have developed leukemia. However, these are rare cases. People with AB negative blood do not need to worry about transfusions.

2. AB negative blood is present in less than 1% of individuals worldwide.

The population of people with AB negative blood is usually around 0.05%. Not everyone has AB negative blood. 3. AB negative blood is commonly found in Northern Europe.

3. AB negative blood is one of the oldest blood types.

Blood types date back thousands of years ago. The oldest known record of blood typing was documented in ancient Egypt. The Egyptians recorded that they had three different blood types: O+, B-, and AB-. These records show that AB negative blood existed before modern medicine.


There are many benefits to having AB negative blood. For one, it's scarce, making you a coveted donor.

●   AB negative blood is also the universal donor, meaning it can be given to any patient needing a transfusion. This is a huge benefit, especially in emergencies when time is of the essence.

●   AB negative blood also doesn't contain antibodies, so patients can receive multiple transfusions without developing harmful reactions.

●   AB negative blood is often used in emergencies because it's compatible with other blood types. And because it's so rare, there's always a demand for it. Only about 7% of the population has AB-negative blood, so it's always in high demand.

●   AB negative blood is also vital for medical research because it's the only blood type that can be used to create universal antibodies.

So if you have AB-negative blood, make sure to donate whenever you can! It could save someone's life.

What are the Risks of AB Negative Blood?

AB Negative blood is the blood that contains no antibodies (the body's defense mechanism).

There are many reasons why people have AB-negative blood, including genetics, immune system defects, and autoimmune disorders.

Having AB-negative blood does not mean you cannot get sick; however, if you do get sick, you may need to receive transfusions to help fight off infections.

Some people who have AB negative blood do not experience problems. However, some people with AB-negative red cells develop severe illness after receiving a blood transfusion.

Symptoms include fever, chills, nausea, vomiting, diarrhea, abdominal pain, and jaundice. People with AB negative blood should avoid donating blood unless they have been tested extensively before donation.

AB-Negative blood is rare, only occurring in 1 out of every 16,000 people. To receive AB-Negative blood, you would have to have parents who are both AB-Negative. If you do not have either AB- parent, you cannot receive AB- Blood.

How Can I Donate AB Negative Blood?

So how can you donate AB-negative blood? It's pretty simple. You can donate your blood to your local blood bank or donation center. They'll test to ensure that it matches the blood type of the patient who needs it, and then it will be stored until it's needed.

If you're interested in donating your blood or participating in medical research, don't hesitate to contact your local blood bank or medical center. They would be more than happy to talk to you about how you can help.

Donating blood is a great way to help save lives; anyone can do it! So if you have AB-negative blood, please consider donating!

Here's the list of blood types in decreasing order of disease resistance: 

1. O Positive

The o positive blood type is the most resistant to disease and is the universal donor. It is also the most abundant blood type in the world. People with o positive blood have higher antibodies that help fight off bacteria and viruses.

2. A Positive

It is the second most common blood type and is often associated with athletic people. These people tend to be stronger than others and are also more likely to survive heart attacks. 

3. B Positive

People with B positive blood have a lower risk of diabetes. They are also more resistant to infections and tend to live longer lives.

4. AB Negative

AB-negative blood comes in a variety of different forms. It is sometimes referred to as the universal recipient. Those with this blood type are considered rare and often have severe allergies.

5. Rh Negative

Rh negative blood is the least common type and tends to be more aggressive than others. There are many myths about RH negative blood, including that they are prone to mental illness and are not good at sports.

People with AB-negative blood do get sick more often than others. But they still get sick less often than those with other blood types. Today, people with AB-negative blood live just as long as everyone else.

AB- and Sickle Anemia

People with AB negative blood are usually born without any signs of the disease. However, they may develop the disease if they inherit the trait from parents with the same blood type.

The risk of getting sickle cell anemia increases with each generation.

Many factors affect the likelihood of a child inheriting sickle cell anemia. These factors include the racial background of the parents, the mother's age when she gives birth, etc. Having AB negative blood is hereditary, meaning that people who carry the trait are carriers. As long as one parent carries the trait, there is a 50/50 chance their offspring will be affected by the disease.

Final Words

People with AB-negative blood cannot produce antibodies that fight bacteria. But don't worry! If you're AB-negative, you probably won't get sick much. 

Nowadays, medical technology has advanced significantly and has all the resources and treatments necessary to assist persons with AB- to enjoy long and healthy lives.

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