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An ovarian cyst is a fluid-filled sac within the ovary. Often they cause no symptoms. Occasionally they may produce bloating, lower abdominal pain, or lower back pain. The majority of cysts are harmless. If the cyst either breaks open or causes twisting of the ovary, it may cause severe pain. This may result in vomiting or feeling faint.

Most ovarian cysts are related to ovulation, being either follicular cysts or corpus luteum cysts. Other types include cysts due to endometriosis, dermoid cysts, and cystadenomas. Many small cysts occur in both ovaries in polycystic ovarian syndrome. Pelvic inflammatory disease may also result in cysts. Rarely, cysts may be a form of ovarian cancer. Diagnosis is undertaken by pelvic examination with an ultrasound or other testing used to gather further details.

Often, cysts are simply observed over time. If they cause pain, medications such as paracetamol (acetaminophen) or ibuprofen may be used. Hormonal birth control may be used to prevent further cysts in those who are frequently affected. However, evidence does not support birth control as a treatment of current cysts. If they do not go away after several months, get larger, look unusual, or cause pain, they may be removed by surgery.
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Osteoporosis is a disease where increased bone weakness increases the risk of a broken bone. It is the most common reason for a broken bone among the elderly. Bones that commonly break include the vertebrae in the spine, the bones of the forearm, and the hip. Until a broken bone occurs there are typically no symptoms. Bones may weaken to such a degree that a break may occur with minor stress or spontaneously. Chronic pain and a decreased ability to carry out normal activities may occur following a broken bone.

Osteoporosis may be due to lower than normal bone mass and greater than normal bone loss. Bone loss increases after menopause due to lower levels of estrogen. Osteoporosis may also occur due to a number of diseases or treatments including alcoholism, anorexia, hyperthyroidism, kidney disease, and surgical removal of the ovaries. Certain medications increase the rate of bone loss including some antiseizure medications, chemotherapy, proton pump inhibitors, selective serotonin reuptake inhibitors, and glucocorticosteroids. Not enough exercise and smoking are also risk factors. Osteoporosis is defined as a bone density of 2.5 standard deviations below that of a young adult. This is typically measured by dual-energy X-ray absorptiometry at the hip.
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As an O Positive donor you are incredibly important to maintaining the blood supply in our community. O Positive is the most common blood type and therefore needed by so many patients.

Annually, more than 120,000 units of blood, platelets and plasma are required to meet the needs of the hospitals we serve, and your blood type is crucial to maintaining an adequate supply. We are grateful to you for so willingly giving the “gift of life”, and through your continued commitment, we are able to maintain our heritage of service to those in need. 1 in 3 people have O+ blood (approximately 37.4% of the population).


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Occupational rehabilitation is the process of restoring function to injured workers so they can return to work. Rehabilitation professionals assess the needs of the person and the demands of the workplace in order to develop a plan of action to get the employee back to work that is suitable and safe for him as soon as possible. Depending on the type of injury, the individual may have to be trained in a new line of work.

A number of professionals are involved in the practice of occupational rehabilitation. Doctors, physiotherapists, occupational therapists, psychologists and massage therapists all have a different role in the rehabilitation of injured workers. Some of the problems treated by these clinicians are amputations, overuse injuries, back pain, neck pain, headaches, fractures, spinal cord injuries, and a host of other injuries.

Increased computer usage has resulted in a growing number of people seeking occupational rehabilitation because of common overuse conditions such as carpal tunnel syndrome, tendonitis, as well as problems brought on by poor sustained postures such as thoracic outlet syndrome or cervical headaches. Other common work injuries are lower back problems such as intervertebral disc bulges especially among those who work with heavy machinery. Physiotherapists and occupational therapists work together to improve the employee's posture (standing as well as sitting), the ergonomics of the work place and the way the individual performs his duties. Many problems like shoulder, back and neck pain, which were believed to be chronic, have been improved by making adjustments in workplace ergonomics and posture and through exercise programmes to restore correct muscle balance and joint alignment.

Active rehabilitation programmes in gym-based settings are a proactive way to rehabilitate injured workers. Once the initial injury has been treated by the physiotherapist in the clinic, many physiotherapists are now designing and supervising exercise programmes in local gymnasiums. These exercise programmes aim to accelerate the return of strength and function of the injured workers and prevent re-injury on their return to work, often with excellent results. Many patients finish the rehabilitation programmes stronger and fitter than before they were even injured and with a renewed passion for exercise!

By participating in active rehabilitation, injured workers can prevent loss of wages due to injuries and can enjoy a more productive working environment. Employers can preserve their bottom line by avoiding decreased man-hours and ongoing medical expenses. With a physiotherapy prescribed rehabilitation programme everyone benefits.

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Osteoarthritis is the most common form of arthritis, affecting millions of people worldwide. It occurs when the protective cartilage on the ends of your bones wears down over time.

Although osteoarthritis can damage any joint in your body, the disorder most commonly affects joints in your hands, knees, hips and spine.

Osteoarthritis symptoms can usually be effectively managed, although the underlying process cannot be reversed. Staying active, maintaining a healthy weight and other treatments may slow progression of the disease and help improve pain and joint function.

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Obesity traditionally has been defined as a weight at least 20% above the weight corresponding to the lowest death rate for individuals of a specific height, gender, and age (ideal weight). Twenty to forty percent over ideal weight is considered mildly obese; 40-100% over ideal weight is considered moderately obese; and 100% over ideal weight is considered severely, or morbidly, obese. More recent guidelines for obesity use a measurement called BMI (body mass index) which is the individual's weight multiplied by 703 and then divided by twice the height in inches. BMI of 25.9-29 is considered overweight; BMI over 30 is considered obese. Measurements and comparisons of waist and hip circumference can also provide some information regarding risk factors associated with weight. The higher the ratio, the greater the chance for weight-associated complications. Calipers can be used to measure skin-fold thickness to determine whether tissue is muscle (lean) or adipose tissue (fat).
Much concern has been generated about the increasing incidence of obesity among Americans. Some studies have noted an increase from 12% to 18% occurring between 1991 and 1998. Other studies have actually estimated that a full 50% of all Americans are overweight. The World Health Organization terms obesity a worldwide epidemic, and the diseases which can occur due to obesity are becoming increasingly prevalent.
Excessive weight can result in many serious, potentially life-threatening health problems, including hypertension, Type II diabetes mellitus (non-insulin dependent diabetes), increased risk for coronary disease, increased unexplained heart attack, hyperlipidemia, infertility, and a higher prevalence of colon, prostate, endometrial, and, possibly, breast cancer. Approximately 300,000 deaths a year are attributed to obesity, prompting leaders in public health, such as former Surgeon General C. Everett Koop, M.D., to label obesity "the second leading cause of preventable deaths in the United States."

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Obsessive-compulsive disorder (OCD) is an anxiety disorder characterized by uncontrollable, unwanted thoughts and repetitive, ritualized behaviors you feel compelled to perform. If you have OCD, you probably recognize that your obsessive thoughts and compulsive behaviors are irrational—but even so, you feel unable to resist them and break free.

Like a needle getting stuck on an old record, OCD causes the brain to get stuck on a particular thought or urge. For example, you may check the stove 20 times to make sure it’s really turned off, or wash your hands until they’re scrubbed raw.

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Oil pulling, also known as "kavala" or "gundusha," is an ancient Ayurvedic dental technique that involves swishing a tablespoon of oil in your mouth on an empty stomach for around 20 minutes. This action supposedly draws out toxins in your body, primarily to improve oral health but also to improve your overall health

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Greasy hair is a hair condition which is common in humans, one of four main types of hair conditioning— normal, greasy, dry and greasy dry. ... A chronic condition of greasy hair may often accompany chronic greasy skin conditions on the face and body and oily skin and acne.

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It can be a natural consequence of the ageing process, as sebum production slows down. oily skin. Oily skin is characterised by an increased amount of lipids on the skin surface due to overactive sebaceous glands. It is shiny and thick, often with enlarged pores. Oily skin is prone to blackheads and other blemishes.

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When You wake up with a stench of onion still on your breath and cant get rid of it all day, even after plentiful brushing of teeth.

When you eat foodage containing onion and cannot get rid of the stench from your breath.

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The pores in the skin become open when the skin is warm or when the pore is forced open by being squeezed. Opening the pores on the face is a good thing to do during the cleansing process, which should be completed daily. The pores can be opened simply by washing the face with warm water, steaming the face in the shower, or applying a warm, damp towel to the face. Once the pores are open, the face can be cleaned in order to clear out the pores and keep the skin healthy.

After the open pores have been cleaned, they can be disinfected with an astringent, which should be applied with a cotton ball or cotton pad. Astringent is especially useful for people with acne, people with oily skin, and people whose skin gets dirty or grimy on a daily basis. It can be too irritating, however, for people with dry or sensitive skin. After the astringent is applied, the face can be rinsed with cold water, which will close the pores once again.


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Occupational asthma is asthma that's caused or worsened by breathing in chemical fumes, gases, dust or other substances on the job. Like other types of asthma, occupational asthma can cause chest tightness, wheezing and shortness of breath.When treated early, occupational asthma may be reversible. Long-term exposure to allergy-causing substances can cause worsening symptoms and lifelong asthma.Treatment for occupational asthma is similar to treatment for other types of asthma, and it generally includes taking medications to reduce symptoms. But the only sure way to eliminate your symptoms and prevent lung damage due to occupational asthma is to avoid whatever's triggering it.

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Ocular rosacea is inflammation that causes redness, burning and itching of the eyes. It often develops in people who have rosacea, a chronic skin condition that affects the face. Sometimes ocular, or eye, rosacea is the first sign that you may later develop the facial type.Ocular rosacea (roe-ZAY-she-uh) primarily affects adults between the ages of 30 and 50. It seems to develop in people who tend to blush and flush easily.Medications and a good eye-care routine can help control the signs and symptoms. But treatment doesn't cure ocular rosacea. It often recurs after an apparent remission.

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Oligodendrogliomas are generally soft, grayish-pink tumors. They often contain mineral deposits (called calcifications), areas of hemorrhage, and/or cysts. Under the microscope, these tumor cells appear to have “short arms,” or a fried-egg shape.

Sometimes oligodendrogliomas are mixed with other cell types. These tumors may be graded using an “A to D” system, which is based on microscopic features of the individual tumor cells. The grade indicates how quickly the tumor cells reproduce and how aggressive the tumor is.

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Optic neuritis is an inflammation that damages the optic nerve, a bundle of nerve fibers that transmits visual information from your eye to your brain. Pain and temporary vision loss in one eye are common symptoms of optic neuritis.

Optic neuritis is linked to multiple sclerosis (MS), a disease that causes inflammation and damage to nerves in your brain and spinal cord. Signs and symptoms of optic neuritis can be the first indication of multiple sclerosis, or they can occur later in the course of MS. Besides MS, optic neuritis can occur with other infections or immune diseases, such as lupus.

Most people who have a single episode of optic neuritis eventually recover their vision. Treatment with steroid medications may speed up vision recovery after optic neuritis.

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Lichen planus is an itchy skin rash that is caused by an immune response. It can occur anywhere on your skin.oral lichen planusIn cases of oral lichen planus, the mucous membranes inside your mouth are the only area affected. Oral lichen planus presents symptoms different from other cases of lichen planus. Instead of a rash, people may experience swollen tissues, white patches, and open sores.Oral lichen planus isn’t contagious, and it can’t be spread to another person.

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Oral thrush — also called oral candidiasis (kan-dih-DIE-uh-sis) — is a condition in which the fungus Candida albicans accumulates on the lining of your mouth. Candida is a normal organism in your mouth, but sometimes it can overgrow and cause symptoms.Oral thrush causes creamy white lesions, usually on your tongue or inner cheeks. Sometimes oral thrush may spread to the roof of your mouth, your gums or tonsils, or the back of your throat.Although oral thrush can affect anyone, it's more likely to occur in babies and older adults because they have reduced immunity; in other people with suppressed immune systems or certain health conditions; or people who take certain medications. Oral thrush is a minor problem if you're healthy, but if you have a weakened immune system, symptoms may be more severe and difficult to control.


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Orchitis (or-KIE-tis) is an inflammation of one or both testicles. It is usually caused by a bacterial infection or by the mumps virus.Bacterial orchitis can be caused by sexually transmitted infections (STIs), particularly gonorrhea or chlamydia. Bacterial orchitis often results from epididymitis, an inflammation of the coiled tube (epididymis) at the back of the testicle that stores and carries sperm. In that case, it's called epididymo-orchitis.Orchitis causes pain and can affect fertility. Medication can treat the causes of bacterial orchitis and can ease some signs and symptoms of viral orchitis. But it may take several weeks for scrotal tenderness to disappear.

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The bones of children and adolescents possess a special area where the bone is growing called the growth plate. Growth plates are areas of cartilage located near the ends of bones. When a child is fully grown, the growth plates harden into solid bone.Some growth plates serve as attachment sites for tendons, the strong tissues that connect muscles to bones. A bony bump called the tibial tubercle covers the growth plate at the end of the tibia. The group of muscles in the front of the thigh (called the quadriceps) attaches to the tibial tubercle.When a child is active, the quadriceps muscles pull on the patellar tendon which in turn, pulls on the tibial tubercle. In some children, this repetitive traction on the tubercle leads to inflammation of the growth plate. The prominence, or bump, of the tibial tubercle may become very pronounced.

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Osteochondritis dissecans (OCD) is a condition that develops in joints, most often in children and adolescents. It occurs when a small segment of bone begins to separate from its surrounding region due to a lack of blood supply. As a result, the small piece of bone and the cartilage covering it begin to crack and loosen.The most common joints affected by osteochondritis dissecans are the knee, ankle and elbow, although it can also occur in other joints. The condition typically affects just one joint, however, some children can develop OCD in several joints.In many cases of OCD in children, the affected bone and cartilage heal on their own, especially if a child is still growing. In grown children and young adults, OCD can have more severe effects. The OCD lesions have a greater chance of separating from the surrounding bone and cartilage, and can even detach and float around inside the joint. In these cases, surgery may be necessary.


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Osteosarcoma is the most common type of cancer that develops in bone. Like the osteoblasts in normal bone, the cells that form this cancer make bone matrix. But the bone matrix of an osteosarcoma is not as strong as that of normal bones.Most osteosarcomas occur in children and young adults. Teens are the most commonly affected age group, but osteosarcoma can occur at any ageIn children and young adults, osteosarcoma usually develops in areas where the bone is growing quickly, such as near the ends of the long bones. Most tumors develop in the bones around the knee, either in the distal femur (the lower part of the thigh bone) or the proximal tibia (the upper part of the shinbone). The proximal humerus (the part of the upper arm bone close to the shoulder) is the next most common site. However, osteosarcoma can develop in any bone, including the bones of the pelvis (hips), shoulder, and jaw. This is especially true in older adults.


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Osteomyelitis is an infection of the bone, a rare but serious condition. Bones can become infected in a number of ways: Infection in one part of the body may spread through the bloodstream into the bone, or an open fracture or surgery may expose the bone to infection.

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As an O Positive donor you are incredibly important to maintaining the blood supply in our community. O Positive is the most common blood type and therefore needed by so many patients. Annually, more than 120,000 units of blood, platelets and plasma are required to meet the needs of the hospitals we serve, and your blood type is crucial to maintaining an adequate supply. We are grateful to you for so willingly giving the “gift of life”, and through your continued commitment, we are able to maintain our heritage of service to those in need. 1 in 3 people have O+ blood (approximately 37.4% of the population)


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Ophthalmology is a branch of medicine dealing with the diagnosis, treatment and prevention of diseases of the eye and visual system. The eye, its surrounding structures and the visual system can be affected by a number of clinical conditions. Ophthalmology involves diagnosis and therapy of such conditions, along with microsurgery. Eye health services are becoming more and more important as the UK population ages. An ageing population means there are more and more incidences of age-related diseases of the eye, such as age-related macular degeneration. These eye diseases can be successfully treated if caught early, and can be managed effectively with existing treatments and medicines. Cataracts are the main cause of impaired vision worldwide, and in England and Wales it is estimated that around 2.5 million people aged 65 or older have some degree of visual impairment caused by cataracts. Cataract surgery is the second most common operation performed in the NHS in England – over 300,000 procedures are performed each year. Patients and members of the general public can view more information about eye conditions and treatments in our ‘For Patients‘ section.


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Spherocytes are osmotically fragile cells that rupture more easily in a hypotonic solution than do normal RBCs. Because they have a low surface area:volume ratio, they lyse at a higher osmolarity than do normal discocyte (RBCs). Cells that have a larger surface area:volume ratio, such as target cells or hypochromic cells are more resistant to lysing. After incubation, an increase in hemolysis is seen in spherocytes. Hereditary spherocytosis typically has greater number of spherocytes than other causes of spherocytosis. Therefore, the degree of lysis is usually more pronounced, but this is not always the case. Some rare disorders can also cause marked fragility and hereditary spherocytosis cases can display moderate fragility.
Spherocytes are osmotically fragile cells that rupture more easily in a hypotonic solution than do normal RBCs. Because they have a low surface area:volume ratio, they lyse at a higher osmolarity than do normal discocyte (RBCs). Cells that have a larger surface area:volume ratio, such as target cells or hypochromic cells are more resistant to lysing. After incubation, an increase in hemolysis is seen in spherocytes. Hereditary spherocytosis typically has greater number of spherocytes than other causes of spherocytosis. Therefore, the degree of lysis is usually more pronounced, but this is not always the case. Some rare disorders can also cause marked fragility and hereditary spherocytosis cases can display moderate fragility.

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Osteocalcin, or bone Gla protein (BGP), is the major noncollagenous protein of bone matrix. It has a molecular weight of approximately 5.8 kilodaltons and consists of 49 amino acids, including three residues of γ-carboxyglutamic acid. Osteocalcin is synthesized in bone by osteoblasts. After production, it is partly incorporated into the bone matrix and partly delivered to the circulatory system. The precise physiological function of osteocalcin is still unclear. A large number of studies have shown that the circulating level of osteocalcin reflects the rate of bone formation.
Determination of serum osteocalcin has proven to be valuable as an aid in identifying women at risk of developing osteoporosis, for monitoring bone metabolism during perimenopause and postmenopause, and during antiresorptive therapy.



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Oxalate (Urine)is a urine test to see whether you have a high level of the chemical oxalate in your urine. Oxalate is a natural end product of metabolism in the body. It should leave your body through your urine. If your oxalate levels are too high, the extra oxalate can combine with calcium to form kidney stones. These stones are hard masses of chemicals that can get stuck in the urinary tract. They commonly cause severe pain. Calcium-oxalate kidney stones are the most common type. Higher levels of oxalate may be caused by eating foods high in oxalate, or by your body absorbing or making too much oxalate.
You may need this test if you have kidney stones often. Your healthcare provider might order this test to help him or her make a recommendation on treatment. It may also be used to find out how well limiting the amount of oxalate in your food is working. You might have this test to see whether you have a rare inherited condition called primary hyperoxaluria and are at risk of developing kidney stones. 

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